Cytotoxic T lymphocytes (CTLs) represent key immune effectors of the host response against chronic viruses, due to their cytotoxic response to virus-infected cells.In response to this selection pressure, viruses may accumulate escape mutations that evade CTL-mediated control.To study the emergence of CTL escape mutations, we employed the murine chr
Abstract Background A plethora of prognostic biomarkers for esophageal squamous cell carcinoma (ESCC) that have hitherto been reported are challenged with low reproducibility due to high molecular heterogeneity of ESCC.The purpose of this study was to identify the optimal biomarkers for ESCC using machine learning algorithms.Methods Biomarkers rela
Eclipse naevi are a kind of signature naevi that are mostly observed on trunks of adults and on scalps of children.As they can have some of the criteria for melanoma and can be difficult to follow up especially when they are located on scalp, removal might be recommended frequently by dermatologists.However they are actually benign and they only ne
ABSTRACT Decision support for nutrient application remains an enigma if based on soil nutrient analysis.If the crop could be used as an Vintage Tees auxiliary indicator, the plant nutrient status during different growth stages could complement the soil test, improving the fertilizer recommendation.Nutrient absorption and partitioning in the plant a